Review



ml 141  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    MedChemExpress ml 141
    Ml 141, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML141/pmc12020991-217-4-12
    Average 95 stars, based on 42 article reviews
    ml 141 - by Bioz Stars, 2026-10
    95/100 stars

    Images

    Related Articles

    other:

    Article Title: In vivo investigation of PEDV transmission via nasal infection: mechanisms of CD4 + T-cell-mediated intestinal infection
    Article Snippet: CT7758 (HY-70073), Y-27632 (HY-10071), ML-141 (HY-12755), and IPA3 (HY-15663) were purchased from MCE (New Jersey, USA).

    Article Title: In vivo investigation of PEDV transmission via nasal infection: mechanisms of CD4 + T-cell-mediated intestinal infection.
    Article Snippet: CT7758 (HY-70073), Y-27632 (HY-10071), ML-141 (HY-12755), and IPA3 (HY-15663) were purchased from MCE (New Jersey, USA).



    Similar Products

    ml 141  (MedChemExpress)
    95
    MedChemExpress ml 141
    Ml 141, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML141/pmc12020991-217-4-12
    Average 95 stars, based on 1 article reviews
    ml 141 - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    chemistry biology  (Tocris)
    95
    Tocris chemistry biology
    Chemistry Biology, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/us12569494-88-123-141
    Average 95 stars, based on 1 article reviews
    chemistry biology - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    cdc42 rho family gtpase  (Tocris)
    95
    Tocris cdc42 rho family gtpase
    Cdc42 Rho Family Gtpase, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/us12569494-88-135-141
    Average 95 stars, based on 1 article reviews
    cdc42 rho family gtpase - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    ml 141  (Tocris)
    95
    Tocris ml 141
    Ml 141, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/bio_rxiv__64898__2026__01__30__702717-369-26-29
    Average 95 stars, based on 1 article reviews
    ml 141 - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    s7008 ml141  (Tocris)
    95
    Tocris s7008 ml141
    S7008 Ml141, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/pm41530254-154-56-59
    Average 95 stars, based on 1 article reviews
    s7008 ml141 - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    ml141  (Tocris)
    95
    Tocris ml141
    CD13-mediated FAK/Src/IQGAP1/ARF6 signaling promotes protrusion formation. ( a ) Treatment with inhibitors of major actin-organizing proteins such as FAK (FAK14; 20 μM), Src (PP2; 10 μM) or Cdc42 <t>(ML141;</t> 20 μM) significantly inhibits protrusion formation in WT KSCs, indicating that these proteins are critical for regulating actin cytoskeletal proteins in the formation of protrusions. ( b ). Representative images showing IQGAP1 or ARF6 (green) and phalloidin (actin; red) staining under CM or crosslinking (mAb 452; 1.8 µg/mL) conditions. ( c - d ) Quantification of Pearson Correlation Coefficient (PCC) between IQGAP1 and phalloidin ( c ) and ARF6 and phalloidin ( d ) staining following treatment with either CM or mAb 452. Treatment with mAb 452 significantly increased the correlation between IQGAP1 and phalloidin as well as ARF6 and phalloidin at the membrane. Data are represented as mean ± standard error and consists of at least three independent experiments with at least 5–10 images taken per treatment condition. *p < 0.05.
    Ml141, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/pmc12880977-9-0-5
    Average 95 stars, based on 1 article reviews
    ml141 - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    tocris 4266 astressin 2b  (Tocris)
    95
    Tocris tocris 4266 astressin 2b
    CD13-mediated FAK/Src/IQGAP1/ARF6 signaling promotes protrusion formation. ( a ) Treatment with inhibitors of major actin-organizing proteins such as FAK (FAK14; 20 μM), Src (PP2; 10 μM) or Cdc42 <t>(ML141;</t> 20 μM) significantly inhibits protrusion formation in WT KSCs, indicating that these proteins are critical for regulating actin cytoskeletal proteins in the formation of protrusions. ( b ). Representative images showing IQGAP1 or ARF6 (green) and phalloidin (actin; red) staining under CM or crosslinking (mAb 452; 1.8 µg/mL) conditions. ( c - d ) Quantification of Pearson Correlation Coefficient (PCC) between IQGAP1 and phalloidin ( c ) and ARF6 and phalloidin ( d ) staining following treatment with either CM or mAb 452. Treatment with mAb 452 significantly increased the correlation between IQGAP1 and phalloidin as well as ARF6 and phalloidin at the membrane. Data are represented as mean ± standard error and consists of at least three independent experiments with at least 5–10 images taken per treatment condition. *p < 0.05.
    Tocris 4266 Astressin 2b, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/pmc12478151__pnas%2E2504151122%2Esapp-91-25-25
    Average 95 stars, based on 1 article reviews
    tocris 4266 astressin 2b - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier
    l3000015 ml141 tocris  (Tocris)
    95
    Tocris l3000015 ml141 tocris
    CD13-mediated FAK/Src/IQGAP1/ARF6 signaling promotes protrusion formation. ( a ) Treatment with inhibitors of major actin-organizing proteins such as FAK (FAK14; 20 μM), Src (PP2; 10 μM) or Cdc42 <t>(ML141;</t> 20 μM) significantly inhibits protrusion formation in WT KSCs, indicating that these proteins are critical for regulating actin cytoskeletal proteins in the formation of protrusions. ( b ). Representative images showing IQGAP1 or ARF6 (green) and phalloidin (actin; red) staining under CM or crosslinking (mAb 452; 1.8 µg/mL) conditions. ( c - d ) Quantification of Pearson Correlation Coefficient (PCC) between IQGAP1 and phalloidin ( c ) and ARF6 and phalloidin ( d ) staining following treatment with either CM or mAb 452. Treatment with mAb 452 significantly increased the correlation between IQGAP1 and phalloidin as well as ARF6 and phalloidin at the membrane. Data are represented as mean ± standard error and consists of at least three independent experiments with at least 5–10 images taken per treatment condition. *p < 0.05.
    L3000015 Ml141 Tocris, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ml+141/ML+141/pm40930094-208-126-128
    Average 95 stars, based on 1 article reviews
    l3000015 ml141 tocris - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    CD13-mediated FAK/Src/IQGAP1/ARF6 signaling promotes protrusion formation. ( a ) Treatment with inhibitors of major actin-organizing proteins such as FAK (FAK14; 20 μM), Src (PP2; 10 μM) or Cdc42 (ML141; 20 μM) significantly inhibits protrusion formation in WT KSCs, indicating that these proteins are critical for regulating actin cytoskeletal proteins in the formation of protrusions. ( b ). Representative images showing IQGAP1 or ARF6 (green) and phalloidin (actin; red) staining under CM or crosslinking (mAb 452; 1.8 µg/mL) conditions. ( c - d ) Quantification of Pearson Correlation Coefficient (PCC) between IQGAP1 and phalloidin ( c ) and ARF6 and phalloidin ( d ) staining following treatment with either CM or mAb 452. Treatment with mAb 452 significantly increased the correlation between IQGAP1 and phalloidin as well as ARF6 and phalloidin at the membrane. Data are represented as mean ± standard error and consists of at least three independent experiments with at least 5–10 images taken per treatment condition. *p < 0.05.

    Journal: Scientific Reports

    Article Title: CD13 activation assembles phosphoinositide (PI) signaling complexes to regulate the actin cytoskeleton

    doi: 10.1038/s41598-026-35022-6

    Figure Lengend Snippet: CD13-mediated FAK/Src/IQGAP1/ARF6 signaling promotes protrusion formation. ( a ) Treatment with inhibitors of major actin-organizing proteins such as FAK (FAK14; 20 μM), Src (PP2; 10 μM) or Cdc42 (ML141; 20 μM) significantly inhibits protrusion formation in WT KSCs, indicating that these proteins are critical for regulating actin cytoskeletal proteins in the formation of protrusions. ( b ). Representative images showing IQGAP1 or ARF6 (green) and phalloidin (actin; red) staining under CM or crosslinking (mAb 452; 1.8 µg/mL) conditions. ( c - d ) Quantification of Pearson Correlation Coefficient (PCC) between IQGAP1 and phalloidin ( c ) and ARF6 and phalloidin ( d ) staining following treatment with either CM or mAb 452. Treatment with mAb 452 significantly increased the correlation between IQGAP1 and phalloidin as well as ARF6 and phalloidin at the membrane. Data are represented as mean ± standard error and consists of at least three independent experiments with at least 5–10 images taken per treatment condition. *p < 0.05.

    Article Snippet: ML141 , 20 μM , Tocris; 4266.

    Techniques: Staining, Membrane